A vibrator is to induce prostaglandin E2 release in facilitating and triggering orgasm, but excessive orgasm (multiple orgasms in one night) or over-masturbation in one shot burned out her dopamine, acetylcholine, serotonin and GABA nervous systems and exhausted her hypothalamus-pituitary-adrenal/ovarian axis for sexual exhaustion symptoms in the next day, including fibromyalgia, tiredness, fatigue, brain fog, stiffness, etc.

Case Study: A vibrator is to induce prostaglandin E2 release in facilitating and triggering orgasm, but excessive orgasm (multiple orgasms in one night) or over-masturbation in one shot burned out her dopamine, acetylcholine, serotonin and GABA nervous systems and exhausted her hypothalamus-pituitary-adrenal/ovarian axis for sexual exhaustion symptoms in the next day, including fibromyalgia, tiredness, fatigue, brain fog, stiffness, etc.

Reader: 01/07/2008>Dear ActionLove.com,

Can having an orgasm, either normal intercourse or vibrator induced, cause someone with fibromyalgia to have a flare-up the next day, ie. tiredness, fatigue, brain fog, stiffness all over, etc.? I just found out about 6 months ago that I indeed do have Fibromyalgia so I've been studying a lot about it. For yrs. I had trouble reaching orgasm at all so my husband thought it would be nice to get me a vibrator for christmas a couple of yrs. ago. It worked very well but I have slowly started to notice that the next day I am so sore and tired all over. We don't abuse it, once a week if that. Sometimes multiple orgasms in 1 night. Before he got it for me I had tried the showerhead approach but it took too long and wasted too much water so I stopped when we moved into a drought aflicted area. Besides, I have a vibrator now.

I hope this is enough info to help you answer my question. I told my husband that I am not going to have another orgasm until I find out for sure. If this is causing me more trouble than it's worth I will get rid of it altogether. I just need to know so I can proceed accordingly.

Thank you

ActionLove.com: 01/08/2008>Yes, orgasm is a sympathetic nervous Fight or/and Flight response. The nervous responses can be last for many hours or days, depending on how exhausted your hypothalamus-pituitary-adrenal and -ovarian (testicular, for men) axis are, and on the integrity of your brain's dopamine, acetylcholine, serotonin and GABA nervous systems, in conjunction with release of prostaglandins, where prostaglandin E1 for relaxation. healing and elasticity, and prostaglandin E2 is for alarm, inflammation and destruction .
The vibrator mechanically induces excessive prostaglandin E2 production to stimulate the clitoral and G-spot nerves for orgasm. This is the main pricinple of vibrator/massager/waterjet induced orgasm. Prostaglandin E2 inflames the tissues, nerves and blood vessels, stimulates the nerves, and suppresses the neuro-immune system. Thus, excessive prostaglandin E2 in your clitoris, vagina, cervix and uterus will also give a persistent sexual arousal as an inflammatory response. Excessive use of a vibrator can cause pelvic and low-abdomen pains, low back pains, clitoral pains and scarring (for clitoral death, hardening of clitoral tunica albuginea), irregular periods, IBS (irritable bowel syndromes) , urinary incontinence, frequent urination, over-reactive bladder, non-organic UTI (Urinary Tract "Infection" without bacteria or virus), urethral burning sensation, non-organic urethritis, persistent sexual arousal symptoms (with severe sexual exhaustion symptoms - ear ringing, anxiety, and stress), skin irritation, yeast infection, Interstitial Cystitis (IC), blood in urine, Vulvodynia (vulva abrasion)/vestibulitis, cramps, PMS, post-orgasm stress, post-orgas anxiety, leg pain, constipation, bloating, wind, vaginal tender and enlargement, Cervical Laceration, and so on, as listed in
https://actionlove.com/extra/vibrator.htm
The normal orgasm requires the clitoral and G-spot erection resulted from the parasympathetic nervous function (acetylcholine-NO (nitric Oxide-cGMP pathway), the sympathetic nervous function via the adrenergic beta-receptors and the erectile action of prostaglandin E1 on the clitoral/G-spot nerves/tissues/arteries, and the ultimate pituitary oxytocin release for uterine contraction, as described in
https://actionlove.com/extra/tipo.htm
https://actionlove.com/cases/case13447.htm
https://actionlove.com/cases/case14660.htm
and
https://actionlove.com/cases/case15423.htm

The vibrator can exhaust your hypothalamus-pituitary-adrenal and -ovarian axis for erectile and orgasmic dysfunction.
Now, you have to repair the vibrator induced damage.

Orgasm can burn out acetylcholine, serotonin and GABA nervous control/modulation on the sympathetic nervous function, and triggered excessive dopamine-norepinephrine-epinephrine conversion and prolactin release, but dropped the cortisol level too low immediately, but followed by a overshooting of cortisol in next morning with a persistent high prolactin, norepinephrine and epinephrine in the bloodstream. The initial drop of cortisol and dopamine, with a high prolactin level, resulting from orgasm, will block the pituitary-adrenal and -ovarian (testicular function) for deficiency of androgen hormones (DHEA, androstenedione, testosterone, DHT ) for at least few hours for a health person. However, it can trigger an excessive prostaglandin E2 production due to deficiency of androgen hormones and cortisol. The cortisol diurnal mechanism will overshot the cortisol in the following morning due to a high prolactin, norepinephrine and epinephrine level with a low dopamine, serotonin and GABA modulation on the adrenal function. The overshooting cortisol with a high level of prolactin continue blocking the pituitary-adrenal and -ovarian (testicular function) for few days.
That is, initially, the patient will experience orgasm induced Hypocortisolism, followed by Hypercortisolism in next morning.
People with a fibromyalgia condition usually have abnormalities of the hypothalamic-pituitary-gonadal axis, or exhaustion or fatigue of the hypothalamic-pituitary-adrenal and/or ovarian (testicular) axis. The post-orgasm fibromyalgia symptoms in fact are the sexual exhaustion symptoms.
The patients have a low cortisol, DHEA, androstenedione, testosterone, DHT and serotonin level, but a higher prolactin, estrogen, epinephrine or/and norepinephrine level with excessive inflammatory hormone prostaglandin E2 production. A high level of the inflammatory hormone prostaglandin E2 in the bloodstream constantly excites the nerve, particularly the sympathetic, glutamate and histamine nervous systems, for sexual arousal, body inflammation pain, headaches, migraine, allergic responses, fatigue and exhaustion. The patient's orgasm is generally triggered by the prostaglandin E2 release in the clitoris, vagina. cervix and uterus, in conjunction with a hyperactive sympathetic nervous function due to excessive norepinephrine and epinephrine, despite of the deficiency of androgen hormones (DHEA, testosterone and/or DHT) and excess of prolactin.
Excessive cortisol, prolactin, norepinephrine or/and epinephrine with a deficiency of dopamine, acetylcholine, serotonin, DHEA, androstenedione and testosterone give you sexual exhaustion symptoms in the next days - tiredness, fatigue, brain fog, dizziness, hangover, stiffness, no contraction, mood swing, anxiety, stress, cramps, joint rigidity and muscle weakness.
For sexual exhaustion symptoms, please also
https://actionlove.com/cases/case9848.htm
https://actionlove.com/extra/alzheimer.htm
https://actionlove.com/extra/parkinson.htm
His and her post-orgasm sexual exhaustion symptoms - sympathetic nervous panic and inflammatory responses, low back pains, low abdomen pains/cramps, perineum inflammatory pains, and so on, for no sexual orgasm - solution
https://actionlove.com/cases/case13819.htm
Why ejaculation/orgasm causes his mood swing, anger, aggression, anxiety, stress, fatigue, tiredness.... for no more sexual orgasm - On the brain and body chemistry change in response to ejaculation or orgasm.
==> https://actionlove.com/cases/case13755.htm
why ejaculation or sexual orgasm induced awful depression, anxiety, body pains (dull throbbing gallbladder and liver pain) for a few day - Solution
==> https://actionlove.com/cases/case15444.htm
What cause the post-ejaculation and post-orgasm pains, cramps, tightness, joint rigidity and muscle weakness for no more sexual orgasm
==> https://actionlove.com/cases/case15079.htm
Sexual Hangover - Sex or orgasm induced headache, poor mentality, mood swings, dizziness and vertigo - solution for the severe side effects of sexual orgasm
==> https://actionlove.com/cases/case15010.htm

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